Most medical breakthroughs come after years, or even decades, of experiments in high-tech laboratories or academic research centers. But every so often, they are born at the hands of experienced physicians simply rethinking how they do things.
That's what happened last fall when Dr. Robert Wood, a pediatric craniofacial and plastic surgeon at Gillette Children's Specialty Healthcare in St. Paul, decided that something had to be done to reduce the rate of blood transfusions in babies undergoing surgery to correct a birth defect known as craniosynostosis.
The condition, in which the bones of the skull fuse together prematurely, is found in about one of every 2,000 live births. Left alone, it results in misshapen skulls, developmental delays and, sometimes, death. Surgery is the only way to correct it. In some cases, ones done early enough, surgeons can use a procedure known as minimally invasive surgery. But more commonly it requires making a wavy cut into the scalp and peeling back the skin so the bones of the skull can be excised and reshaped.
Wood is one of the most experienced physicians in the United States who perform the complicated procedure known as cranial vault expansion surgery. He said he decided to rethink how it's done after he and his colleagues were discussing blood conservation techniques at a professional meeting in September.
Transfusions are required in more than nine out of 10 craniosynostosis surgeries, according to the medical literature — a rate that matched his own experience, Wood said.
But transfusions themselves can cause problems.
Although the nation's blood supply is very safe from most infectious diseases, transfusion can introduce the possibility of post-surgery infections, fevers or even allergic reactions to the blood — to say nothing of the emotional toll transfusions exact on family members. They can also add to the cost of a procedure — an expense that sometimes falls partly to families with the expansion of high-deductible insurance policies.
Wood and his colleagues at Gillette Children's perform 40 to 60 craniosynostosis procedures a year — more than all other Minnesota hospitals combined in 2012.