Casting Matthew Perry as Sen. Ted Kennedy may seem like a stretch, but the former "Friends" star is just the latest unlikely actor to join America's "royal" family.

Craig T. Nelson

Three years before becoming "Coach," Nelson played Teddy in the 1986 TV movie "The Ted Kennedy Jr. Story," about the senator's son, whose leg was amputated after he developed a rare form of cancer.

Casey Affleck

The Oscar winner got an early chance to show off his Massachusetts accent, playing Robert Kennedy from age 12 to 15 in the 1990 TV miniseries "The Kennedys of Massachusetts." Charles Durning won a Golden Globe as patriarch John "Honey Fitz" Fitzgerald.

Ossie Davis

In the 2002 film comedy "Bubba Ho-Tep," Davis plays a nursing home resident who believes he's JFK — which would seem ludicrous except he's joined by Elvis Presley in a battle against an ancient Egyptian mummy.

Sarah Michelle Gellar

Roma Downey does the heavy lifting in the 1991 TV miniseries "A Woman Named Jackie," but look for pre-vampire slayer Gellar as the teenage Jacqueline Bouvier.

Bruce Dern

Dern will portray Joe Kennedy Sr. in the upcoming indie feature "Chappaquiddick," about his efforts to salvage son Teddy's reputation despite a stroke that had robbed him of the power of speech.