What we know about the 'kraken' COVID variant XBB.1.5 and why it's causing concern

A new COVID-19 variant that was first detected last year has quickly become the dominant strain in the U.S. — and picked up a creepy moniker along the way.

Nicknamed the "kraken variant" by some, it surged through the nation and has now been identified in at least 28 other countries, according to the World Health Organization. Is it more dangerous? Does it spread more easily? And how will it affect China's COVID-19 outbreak?

Here are all your questions, answered.

What is the new variant?

XBB.1.5 is a descendant of the omicron XBB subvariant — which is itself a cross between two earlier strains: BA.2.75 and BA.2.10.1.

The original XBB variant has already caused waves of infection in countries including Singapore and India since the WHO first raised concern about it last October.

How fast is XBB.1.5 spreading?

XBB.1.5 is "the most transmissible subvariant which has been detected yet," said WHO's COVID-19 technical lead, Maria Van Kerkhove, during a news conference on Jan. 4. While only 29 countries have reported cases caused by it, health authorities are warning it could be much more widespread and silently proliferating thanks to a drop-off in testing.

In other countries, the proportion of infections caused by XBB.1.5 has remained lower, although the picture may rapidly change. Estimates from the Wellcome Sanger Institute found that the variant made up around 4% of COVID-19 infections in England as of mid-December, while Canada has found a handful of such cases.

Scientists pointed out that the subvariant has a much stronger affinity to ACE2, a key receptor for the virus, which allows it to bind more easily and boosts its transmissibility.

Is it more dangerous than previous variants?

There haven't been significant differences in severity reported between cases caused by XBB.1.5 and previous variants. Like other strains that concerned scientists, however, XBB.1.5 is attracting attention because it is exhibiting signs of immunity escape. That means it has an ability to evade natural immunity or previous protection provided by vaccines, and reinfect people who have recovered from an earlier bout of COVID-19.

It's unclear if the U.S. experience with XBB.1.5 will extend to other countries. America, unlike many other developed nations, suffers from low vaccination rates. Only 15% of the population aged 5 and above has received an updated bivalent booster dose. The rate is slightly better among the vulnerable elderly population, including those aged 65 and above, with fewer than four in 10 receiving the shot. Hospitalization rates for COVID-19 are already rising, amid a surge in other winter-season infections like influenza.

The WHO plans to release an updated assessment on the variant's risks in the coming days.

Has it reached China yet and what will be its impact?

China, which is going through a major wave of infections after dismantling its stringent "COVID-zero" policy in recent weeks, has yet to report any domestic cases of XBB.1.5. Shanghai has detected three infections caused by the variant and said all were imported cases. But health agencies across the world, including the WHO, have raised concerns that China isn't providing enough genomic sequencing information to come to any definitive conclusions.

In the meantime, the country's COVID-19 wave is being driven by two other omicron strains: BA.5.2 and BF.7. Together they account for 97.5% of all local infections, according to genomic sequencing data from the Chinese Center for Disease Control and Prevention.

Where did the 'kraken' name come from?

COVID-19 variants are currently named by an expert group convened by the WHO. It identifies so-called variants of concern that have potential global public health significance, such as reducing the effectiveness of current pandemic measures, using the Greek alphabet. Previous strains such as alpha, beta and delta fell under the convention.

But the last Greek-named variant, omicron, emerged more than a year ago and left no room for the emergence of other, significantly different strains. Omicron has spawned multiple lineages, including XBB.1.5, and their names stem from a mix of alphabets and numbers known as "Pango."