No. 1 Clemson (7-0, 6-0 ACC) at No. 4 Notre Dame (6-0, 5-0), Saturday at 7:30 p.m. EST (NBC).

Line: Clemson by 5 1/2.

Series record: Clemson leads 3-1.


In what could be the first of several meetings between the two this season, the winner puts itself in the driver's seat for a berth in the ACC title game and the College Football Playoff.


Clemson's top 10 offense against Notre Dame's top 10 defense. Even with Trevor Lawrence sidelined by COVID-19, the Tigers rallied from 18-points down to beat Boston College 34-28 behind true freshman D.J. Uiagalelei. Clemson averages 46.1 points, 341.4 passing yards and 508.0 total yards per game. Led by S Kyle Hamilton, LB Jeremiah Owusu-Koramoah and DE Daelin Hayes, the Irish are allowing just 10.3 points , 173.5 passing yards and 267.2 total yards per game.


Clemson: RB Travis Etienne. The senior, whose 62-yard TD run closed out Clemson's 30-3 victory over the Irish in 2018 CFP Cotton Bowl semifinal, is the ACC's all-time leading rusher with 4,644 yards and has become more of a dual-threat this season with 606 yards rushing and 424 receiving yards.

Notre Dame: QB Ian Book. The fifth-year senior is 26-3 as a starter. He has thrown for 511 yards and three touchdowns in road victories over Pittsburgh and Georgia Tech the last two weeks. He has thrown 129 consecutive passes without an interception.


This is sixth matchup of AP top-5 teams in ACC history. The lower ranked team has won four. ... The only Irish victory in the series, 21-17, came at Clemson during their 1977 national championship season. … Notre Dame's 12-game winning streak is the longest in the FBS. … The Irish's 22-game home winning streak is tied for second among active streaks behind Clemson's 27. … The Tigers have won 39 straight non-bowl games and are 20-1 in November games since 2015. … Saturday's game is Clemson coach Dabo Swinney's 100th ACC regular-season game (83-16). … Notre Dame coach Brian Kelly is seeking his 99th coaching victory at Notre Dame; only Knute Rockne (105) and Lou Holtz (100) have more. ... No. 1 teams are 5-2 at Notre Dame. The last time was 2005 against USC, the "Bush Push" game. The last Irish victory was against Florida State in 1993.