No. 1 Clemson (7-0, 6-0 ACC) at No. 4 Notre Dame (6-0, 5-0), Saturday at 7:30 p.m. EST (NBC).
Line: Clemson by 5 1/2.
Series record: Clemson leads 3-1.
WHAT'S AT STAKE?
In what could be the first of several meetings between the two this season, the winner puts itself in the driver's seat for a berth in the ACC title game and the College Football Playoff.
KEY MATCHUP
Clemson's top 10 offense against Notre Dame's top 10 defense. Even with Trevor Lawrence sidelined by COVID-19, the Tigers rallied from 18-points down to beat Boston College 34-28 behind true freshman D.J. Uiagalelei. Clemson averages 46.1 points, 341.4 passing yards and 508.0 total yards per game. Led by S Kyle Hamilton, LB Jeremiah Owusu-Koramoah and DE Daelin Hayes, the Irish are allowing just 10.3 points , 173.5 passing yards and 267.2 total yards per game.
PLAYERS TO WATCH