PHILADELPHIA – When there finally is an approved vaccine for COVID-19, the first doses should go to front-line health workers in hospitals, nursing homes or home care, as well as first responders like police officers and firefighters, according to new recommendations from the National Academies of Sciences, Engineering and Medicine.

That first-in-line group, which represents 5% of the U.S. population, is critically important for keeping the health system running, but it also faces high risk of getting and transmitting the new virus.

Once more doses are available, people with underlying health problems that put them at “significantly higher risk” for severe disease and death could line up for shots as part of the next phase. That would likely include people with two or more major health problems, such as cancer, chronic kidney disease, chronic obstructive pulmonary disease, obesity, heart disease or diabetes. That group, about 10% of Americans, would also include people 65 and older who live in congregate settings, such as nursing homes, homeless shelters and jails.

A panel assembled by the national academies took on the project at the request of the National Institutes of Health (NIH) and the CDC. It is difficult to know how influential its recommendations will be. Traditionally, the CDC’s Advisory Committee on Immunization Practices recommends who should get vaccines. It has been discussing allocation for months but has not yet made official recommendations.

The academies panel said its recommendations may need to be modified depending on the characteristics of vaccines that prove safe and effective enough for widespread use. Some may be more effective in certain patient groups. Trials of vaccines now in the final phase of testing have not included children.

The 237-page document stresses that it is important that Americans trust that the vaccine is safe. The group called on the government to reach out to minorities and other groups that are often skeptical about vaccines and may be even more concerned now because of political pressure to approve a vaccine quickly.

It also said that public health officials involved in distributing the vaccine need to make it accessible to people who live in poorer neighborhoods and to racial and ethnic groups, such as Blacks, Hispanics and American Indians, that have been disproportionately affected by the virus.

Wide vaccine coverage is considered a crucial step in bringing the pandemic to an end. There are now 149 vaccines in development with four in the last stage of clinical trials. On Friday, Victor Dzau, president of the Academy of Medicine, said a vaccine may be available by the end of 2020 or the beginning of next year, but there won’t be enough doses at first to meet demand.

Members of the panel emphasized the importance of having an independent, nongovernmental group weigh in on vaccine distribution. “This turns out to be so important for the trust factor,” said William Foegge, committee co-chair, emeritus professor of international health at Emory University and former CDC director.

The group decided not to directly target race, but focus instead on factors that contribute to high disease burden among certain minorities.