But Ouimet's victory was only half the story.
Equally an underdog was his caddie, the pint-sized and smart-mouthed Lowery who was playing hooky from school and carrying the bag because his older brother was pinched by a truant officer. Before the playoff, club officials tried to buy Lowery out of the gig; since Ouimet was an amateur, there would be no winnings for Lowery to share.
But Ouimet "stuck with Eddie," cementing a friendship that persisted the rest of their lives.
Their story was the subject of a 2005 Disney movie starring Shia LeBeouf as Ouimet and based on Mark Frost's book, "The Greatest Game Ever Played." A children's book out this year, "Francis and Eddie, the true story of America's underdogs," focuses on the friendship that persisted for the rest of their lives.
Lowery went on to be a caddie master, a newspaper executive, a sports writer and an advertising entrepreneur before moving to California and becoming a successful car dealer. He won the 1927 Massachusetts Amateur and qualified for match play in the U.S. Amateur five times.
He was also a major benefactor of the Francis Ouimet Scholarship Fund.
Ouimet won the U.S. Amateur the next year and again 17 years later. He went on to play in or captain the U.S. Walker Cup team 12 times and was inducted into the Golf Hall of Fame in 1940. He ran a sporting goods store, was a vice president of the Boston Braves and president of the Boston Bruins, and was elected the first American captain of the R&A in 1951.
But he is best remembered for the fund established in 1949 by his friends that has distributed more than $25 million to more than 5,000 students who have provided service to the sport of golf. Among the recipients was Allen Doyle, who played on the PGA Tour and went on to win a $1 million annuity as the leading money winner on the senior tour in 2001.
He donated it to charity.
"What Ouimet did throughout his life, his legacy that he left for people, is that he gave back," said Peter Jacobsen, a seven-time winner on the PGA Tour. "That epitomized what golf and charity is all about."