Minnesota's 20 largest companies together lost $109.7 billion, or 26 percent, of their market values as Wall Street's meltdown went global during the past 10 trading days. The biggest loser: fertilizer giant Mosaic Co., which shed $17.6 billion. Medtronic, Target, 3M, UnitedHealth Group and U.S. Bancorp each lost more than $10 billion. All but three of the stocks hit 52-week lows this week. The list below is ranked by Friday's market value, which is the share price multiplied by the number of shares outstanding.

Source: Bloomberg News