Celcuity, a clinical-stage company developing a cancer drug, had promising clinical trials. Among Minnesota’s public companies, half saw their stock increase this year.
More from MN Fortune 500
Editor's Pick
Caribou Coffee to refocus on cozy cafes instead of drive-thru speed
The Minnesota-founded chain’s new CEO is emphasizing “chalet” coffee shops, a departure from the tiny “cabin” storefronts started in 2019.
December 18, 2025
Why Hormel is struggling to profit off America’s protein obsession
The Austin, Minn.-based company has long made a name for itself selling Spam, Jennie-O turkeys, Planters nuts and more, but high costs have eroded its profits.
December 17, 2025
Hormel leaning on cost cuts, price hikes to boost profits next year
The Spam-maker has experienced a string of tough years, including 2025, but analysts predict a stronger year to come.
December 4, 2025
![Hormel headquarters in Austin, MN. ] GLEN STUBBE * gstubbe@startribune.com Friday September 11, 2015 Despite woes throughout the food industry, partly due to consumers turning away some from processed foods, Hormel has managed to continue prospering -- even though a good part of its business -- Spam, chili -- is about as processed as you can get. But the company's turkey and pork offerings are riding a hot protein trend. And over the past two years, it's made some of the biggest acquisitions in](https://arc.stimg.co/startribunemedia/527MWWMEXAN6BDVVGMMGBOERGU.jpg?&w=252&ar=3:2&fit=crop)
Associated Bank expands Twin Cities footprint with purchase of American National
The Green Bay, Wis.-based bank is picking up six area branches in the $600 million deal.
December 1, 2025
More tech upgrades bump Best Buy’s sales, but home purchases still lag
The Richfield-based retailer posted its second straight quarter of sales growth, but consumer sentiment and competition keep analysts conservative on stock.
November 25, 2025
Incoming CEO is writing Target’s next chapter, including largest store overhaul in a decade
Analysts are wary Michael Fiddelke’s plan won’t be quick enough to stem the Minneapolis-based retailer’s slide.
November 23, 2025
Key takeaways from Target’s pre-holiday report
As tight consumer budgets continue, Target’s sales and profits both declined. The company also is increasing its investment in stores, merchandise and AI.
November 19, 2025
Target’s corporate archivists preserve a century of Minnesota retail history
From past iterations of shopping carts to a salvaged Target Center “T,” these researchers can trace the Minneapolis-based retailer’s roots back to Dayton’s department store in the early 1900s.
November 11, 2025
General Mills CEO keeps a steady hand in turbulent time for Big Food
Eight years in, Jeff Harmening has learned to hold firm to the basics while embracing change at the Golden Valley-based company known for cereal.
November 10, 2025
Fastenal CEO leads with Minnesota modesty and so far is hitting the mark
Dan Florness is known for being frank, and also for facing problems before they show up in results.
November 8, 2025
Hormel cutting 250 jobs through layoffs, buyouts, hiring pause
The corporate restructuring at the Austin-based Spam-maker follows heavy inflation and a dim earnings outlook.
November 4, 2025
Editor's Pick
From more meat to less waste: How Minnesota food companies Cargill, General Mills use AI
Artificial intelligence-backed demand forecasting, supply chain tracking, prototype generating and even holiday commercials from Coca-Cola aim to make the industry more efficient without replacing human workers.
November 4, 2025
