Respiratory medical device maker Vyaire Medical plans to close its plant in Plymouth by June 30, eliminating approximately 50 jobs, according to state officials.

Vyaire Medical, based in Mettawa, Ill., north of Chicago, manufactures and sells products for respiratory problems and surgical anesthesia that generate more than $800 million in annual sales.

On Monday, Vyaire Medical’s owners notified the state of the planned layoffs. Company officials did not return requests for comment.

Vyaire Medical was formed in October 2016 as the respiratory solutions business of large health care supplier BD (Becton, Dickinson and Co.) That month, private-equity funds advised by Apax Partners acquired a majority stake in Vyaire Medical.

“We are pleased with the progress our team has achieved over the past 18 months in establishing Vyaire Medical as a focused and leading global respiratory solutions provider,” Vyaire Medical CEO Dave Mowry said in a news release last month. “Our success in standing up Vyaire Medical as an independent company also has been made possible by the support of BD and the contributions from Apax Partners.”

Apax announced March 19 that it intends to acquire the remaining stake in Vyaire Medical.