A combined Delta and Northwest would have the size and reach that almost guarantees some competitors will respond in kind.
United Airlines, Continental Airlines and American Airlines have already had preliminary discussions about possible combinations of their own, and some in the industry believe a United-Continental tie-up could come quickly, which would create another megacarrier like Delta-Northwest.
That could mean the current six major domestic airlines shrink to three within a year, if regulators consent. That domino effect ups the stakes considerably as the government reviews the Delta-Northwest proposal.
The airlines may have fortuitous timing in trying to sell giant combinations to regulators and passengers. Among the factors: the recent enactment of an "open skies" treaty, which significantly loosens U.S. access for foreign carriers. Many airline executives argue that mergers are needed to survive. Soaring fuel prices have sent smaller carriers to bankruptcy this year, and overseas markets are becoming more competitive and deregulated.
"The competitor now is [across] the globe and not the contiguous 48 states," said Bill Swelbar, an airline analyst at the Massachusetts Institute of Technology.
Establishing a pattern
The Delta-Northwest deal is expected to set a pattern for others in that it will call for few job cuts or route pairings -- the traditional objections such combinations face in getting approval -- and raise the promise of elevating service above its current, often dismal levels, which many passengers view as the equivalent of a bus ride at 35,000 feet.
"If you think the service today isn't very good and the planes are old, maybe the customer would be better off with a bigger company, arguably able to compete on a global scale, arguably more profitable," said airline analyst Patrick Murphy.