Dr. John Noseworthy, CEO, Mayo Clinic

In 2014, the Mayo Clinic set in motion a 20-year, $6 billion economic development project in its hometown of Rochester. The goal is to enhance Mayo's status as a global destination for health care, while growing the local economy.

What happened: A development plan for the Destination Medical Center project should be approved and ready to implement during the first quarter of 2015. During 2014, Mayo expanded its care network subscription service, where hospitals across the country can more easily consult with experts at the clinic. Mayo does not own hospitals that participate in the Mayo Clinic Care Network. The program added member organizations in seven states last year, and membership stands at 31 organizations across 18 states, Puerto Rico and Mexico.