Motorists will have to endure another closure on Hwy. 100 in the southwest-metro area this weekend. But a shutdown of the reversible toll lanes on Interstate 394 may cause the biggest headaches for football, baseball and basketball fans — not to mention Monday morning commuters.

Those are highlights of this weekend’s roadwork preview.

The I-394 project will affect fans heading to Twins games Friday through Sunday at Target Field, the Gophers football game Saturday and the Vikings’ regular season home opener Sunday, both at TCF Bank Stadium, or the Minnesota Lynx playoff game against Los Angeles Friday night at Target Center.

All traffic on I-394 between Hwy. 100 and downtown Minneapolis will share the general traffic lanes. The HOT (high-occupancy toll) lanes will be closed from 7 p.m. Friday until 3 p.m. Monday. Eastbound drivers on Monday morning can expect significant delays and are advised to plan accordingly, according to the Minnesota Department of Transportation (MnDOT).

In addition, a full closure of northbound Hwy. 100 between I-494 and Crosstown Hwy 62 goes into effect at 10 p.m. Friday. Motorists will be detoured until 5 a.m. Monday. This comes in addition to the lane restrictions between Excelsior Boulevard and I-394 in St. Louis Park. More closures are on tap for the next three weekends, MnDOT said.

Meanwhile, a big bike ride in Minneapolis and road construction projects will make it challenging to get to other large events such as the Minnesota Renaissance Festival in Shakopee, St. Paul’s Oktoberfest or Open Streets on Nicollet Avenue between Lake and 46th streets in Minneapolis.

Here are other places you’ll encounter cones and closures:

• In Forest Lake, Hwy. 97 will shut down between Forest Road and Hwy. 61 from 10 p.m. Friday until 5 a.m. Monday.

• County Road 101 will be closed between downtown Shakopee and Hwy. 61 in Chanhassen from 6 p.m. Friday until 9 a.m. Saturday.

• Drivers on I-35E can expect lane closures between I-694 and County Road 96 from Friday through Sunday.

• The ramp from westbound I-94 to southbound I-494 in Maple Grove remains closed until mid-October. I-494 between the Fish Lake Interchange in Maple Grove and I-394 in Minnetonka has lane restrictions and ramp closures at Bass Lake Road.

• Northbound I-35W will be reduced to two lanes at County Road 96 from 5 a.m. to 2 p.m. Saturday. Ramps to and from northbound I-35W and County 96 are closed all weekend.

• Hwy. 10 near Armstrong Boulevard in Ramsey. Armstrong is closed north of Hwy. 10 through October.

• Hwy. 169 between Hwy. 21 and Hwy. 282 in Jordan is reduced to a single lane with a speed limit of 45 miles per hour through late October. Expect heavier traffic due to the Renaissance Festival.

• Hwy. 13 between 2nd Street and Lexington Avenue in Mendota and Lilydale. The detour is via Hwy. 110 and I-35E.

• While the new southbound lanes on the Lafayette Bridge have opened, motorists can still expect periodic lane closures between E. 7th Street and Plato Boulevard. The ramp from southbound I-35E to southbound Hwy. 52 remains closed.

Vehicles will be barred from several Minneapolis parkways from 7 a.m. to 3 p.m. Sunday for the 2015 Minneapolis Bike Tour. The following parkways will be affected: Nokomis, Lake Harriet, Lake Calhoun, Minnehaha, Godfrey, West River, William Berry, Theodore Wirth, Webber, St. Anthony, Cedar Lake and Victory Memorial Drive.