Already missing guard Jimmy Butler for the past 16 games, the Timberwolves went two starters down Sunday when point guard Jeff Teague didn't play because of a sore knee in a 121-97 loss to Utah.
Without either, the Wolves led 9-2 early and trailed by as much as 29 points in the fourth quarter while they played on with Tyus Jones as starter and little-used Aaron Brooks as his backup.
"You know, I don't want to use that as an excuse, when you're down people," Wolves coach Tom Thibodeau said. "I'm disappointed with tonight, but they've fought hard with Jimmy being out. When you're down a player like that, your only chance is with great intensity. So when you lose another guy, you can't go in and think, 'OK, this is good, like we're good.' No, you got to compete on every play. Until we understand that, there will be tough nights."
Backup guard Derrick Rose was available to play Sunday after he missed five games because of a sprained ankle, but he did not.
The Wolves next play Thursday at Denver, which plucked victory from defeat by beating Milwaukee Sunday night.
The Wolves are 8-8 since Butler went down clutching his knee in Houston right after All-Star break.
"When we took the hit with Jimmy, I knew it'd be a long, hard fight," Thibodeau said. "You can't exhale. You can't feel good. You've got to keep swinging. That's the only way this is going to get done. For the most part, these guys have done it. The schedule we had when Jimmy went down, these guys have put up a good fight and they're still fighting.
"I'm disappointed with today's performance. We have to regroup and get ready for the next one."