Seattle 31, Vikings 17
One man's prediction: The Vikings are in much better shape health-wise than last week. Yes, QB Christian Ponder is dealing with a dislocated left shoulder, but several starters are expected to return, including RT Phil Loadholt, S Jamarca Sanford and CB Chris Cook. But the Seahawks are 9-1, own the best defense in the NFL and have a 12-game winning streak at home.
Pick masters
Ponder didn't let an interception on the opening drive of his last start ruin his performance. But he can't take risky chances against a Seattle defense that has the best secondary in the NFL. The Seahawks have forced 22 turnovers, which is tied for second most in the league. They are tied for first with 13 interceptions. Richard Sherman and Earl Thomas have four interceptions apiece.
Running wild
Yes, the NFL has become a passing league, but this game features a couple of heavyweight running backs in Adrian Peterson and Marshawn Lynch. Their statistics are remarkably similar and they both love to punish defenders. Both teams rank in the middle of the pack in run defense, so this is a big challenge for both units. "They're both beasts, that's the way to explain it," Vikings defensive end Jared Allen said. "I love playing against Marshawn. If you can't get up to a game plan against him, he's going to let you know about it. Those two are probably most similar to each other than anyone in the league."
Noisy deal
The Seahawks own the loudest home-field advantage in the NFL at CenturyLink Field. They have won 12 consecutive games at home and are 63-29 there since 2002, the second-best home record in the NFL in that span. Crowd noise is always a factor at CenturyLink. Opponents have committed 127 false start penalties since 2005, the highest number of any venue.
MANO-A-MANO: MATCHUP TO WATCH
Vikings WR Cordarrelle Patterson vs. Seahawks CB Richard Sherman