As osteoporosis transformed her mother's figure, Karen Ryan saw the bone-weakening disease change her mother's affability, too. Along with a slouched posture, it brought a social slump.
With the struggle to find clothes that fit, Ryan said, her mother began to withdraw and became inactive.
But Ryan, a doctor, saw a nonmedical solution that could be the perfect fit for women with osteoporosis: clothing made just for them, designed for comfort and confidence.
Working with a clothing design professor at the University of Minnesota and a powerful scanner equipped with eight lasers, Ryan has created patterns and designs to fit the unique needs of women with osteoporosis. Now she is turning her attention to how to bring the clothing to the mass market.
Osteoporosis characteristically twists spines. As vertebrae easily fracture, the spine essentially collapses to create a distinctive hunched shape, or kyphosis -- complicating the search for garments that fit and flatter.
"It was almost impossible to find [such garments] when I was shopping for my mother," Ryan said. Inspired by her mother's plight, she went back to school to learn how to construct the clothes herself.
In spring 2002, Ryan met with Karen LaBat, a University of Minnesota clothing design professor, to discuss her plans. Ultimately, Ryan landed in a graduate program there.
As she became immersed in her venture, she scaled back hours at her medical practice, eventually shutting its doors.