Study on NFL players gives hope for brain disease treatment

Researchers found tau protein in brains of five living retired NFL players with varying levels of cognitive and emotional problems.

January 23, 2013 at 12:49PM

An insidious, microscopic protein that has been found in the brain tissue of professional football players after death may now be detectable in living people by scanning their brains.

Researchers say they found tau protein in the brains of five living retired National Football League players with varying levels of cognitive and emotional problems.

"It's definite, we found it, it's there," said Dr. Julian Bailes, co-director of the NorthShore Neurological Institute in Evanston, Illinois, and co-author of a new study that identified the tau. "It was there consistently and in all the right places."

Using a scan called positron emission tomography, or PET -- typically used to measure nascent Alzheimer's disease -- researchers injected the players with a radioactive marker that travels through the body, crosses the blood-brain barrier and latches on to tau.

What has stymied researchers for years is that tau can only be uncovered after death. Finding it in living players is considered by many researchers to be the "holy grail" of concussion research, according to Bailes.

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Colleen Stoxen

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Colleen Stoxen oversees hiring, intern programs, newsroom finances, news production and union relations. She has been with the Minnesota Star Tribune since 1987, after working as a copy editor and reporter at newspapers in California, Indiana and North Dakota.

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