Premier League: Tottenham at Manchester United, 6:30 a.m. Saturday, NBCSN. Spurs striker Harry Kane will miss the game, and without its best weapon, Tottenham would do well to earn a draw. That said, Spurs dominated Liverpool last week. A road victory at Old Trafford would do wonders for the team’s confidence.


Serie A: Juventus at AC Milan, 11 a.m. Saturday, beIN. With more than a quarter of the Italian season in the books, it looks like AC Milan probably needs another year before it can climb back into the Serie A elite. Juventus finds itself in an unfamiliar position — third place. This could be a statement game for either team.


Bundesliga: RB Leipzig at Bayern Munich, 11:30 a.m. Saturday, FS2. It’s so far, so good for interim Bayern coach Jupp Heynckes, who has four victories in four games and has Bayern back in a tie atop the German table. These two teams met Wednesday in the German Cup, with Bayern winning on penalties. Leipzig is out for revenge.


MLS: Seattle at Vancouver, 7:30 p.m. Sunday, ESPN. Vancouver nearly won the Western Conference but ended up in third, where it had to play a midweek knockout game against San Jose. Seattle is without Clint Dempsey in the first leg of this two-legged game, so Seattle might hope for a comfortable draw in this one and a victory in the second leg on Thursday.