For University of Minnesota senior Jacob King, the last month has been especially straining as cases rise.
"I am frustrated with people my age. It seems that every week there is a video or photograph of very large parties taking place on campus," King said.
These videos and reports of mask-less parties are particularly stressful for King, 22, who has elderly parents and a brother who is immunocompromised.
"If they catch COVID, it is very likely that all three of them could end up in the hospital," King said. "That is why I wish people could just stop being selfish and stop going to large gatherings. I wish people would wear masks, even if it's in their friend groups."
Making or maintaining friendships is another concern. In Minnesota, known for being insular even before the pandemic, it's particularly tough.
Married mom of four Kirby Hoberg doesn't have family in Minnesota. She and her husband moved to Plymouth from California a couple of years ago, and their own families are in different parts of the country, making seeing loved ones impossible.
"When you get down to COVID bubble circles, everyone here will largely choose their family," Hoberg, 30, said. "We don't really makes the cut."
Hoberg, who acted before her theater was shut down, has watched some of her friends continue to make unsafe choices throughout the course of the pandemic, which can feel isolating.