With an additional 1,714 new COVID-19 infections announced Tuesday by state health officials, Minnesota has surpassed more than 400,000 coronavirus cases.
Twenty-four more deaths were also reported, with 16 among residents of long-term care facilities.
Since the pandemic began in the state in March, 4,896 people have died and 401,011 residents have tested positive for COVID-19, although it is likely that many more have caught the virus but were not tested.
Minnesota Health Commissioner Jan Malcolm said the state could surpass 5,000 total coronavirus deaths this week.
"This follows that big surge in cases that we saw in November," she said.
New case and death counts are typically lower in the beginning of each week, reflecting reduced reporting to the Minnesota Department of Health over the weekend.
But December so far has been the deadliest of the pandemic, with 1,303 deaths reported, surpassing the 1,136 deaths in November.
The state has seen relatively lower case counts over the past several weeks.