Ben Lamm and George Church are thinking big. Their new bioscience and genetics startup is called Colossal, and Colossal's first project is mammoth. Literally.
Lamm, an entrepreneur, and Church, a renowned Harvard geneticist, are planning to "de-extinct" the woolly mammoth — the massive, tusked beast that roamed the cold northern steppes during the Pleistocene. The last mammoth died 4,000 years ago on Wrangel Island, a final frigid outpost in the Arctic Ocean.
In a newspaper interview, Lamm didn't hide his breathless enthusiasm: "I truly believe that Colossal will not only be the first company to bring back extinct species, starting with the woolly mammoth," but also that reintroducing the mammoth will "help slow down carbon emissions in the region and help restore lost ecosystems."
Lamm says Colossal's goal is "not just the successful resurrection of the woolly mammoth, but its full rewilding into the Arctic."
Why do I detect the familiar whiff of snake oil, the heady aroma that attracts headlines and startup funds?
For one thing, this story depends heavily on its sensational Rip Van Winkle quality, the idea that a species that last saw the light of day 4,000 years ago can be reawakened to assume its ecological niche on the Arctic tundra.
In fairness, Lamm and Church don't try very hard to hide this sleight-of-hand. Of course, the woolly mammoth isn't being "resurrected." Colossal will use advanced gene-editing techniques to copy preserved mammoth genes into the genome of an Asian elephant in order to generate in its offspring "increased body fat, characteristic shaggy hair, sebaceous gland development, a domed cranium, shorter ears and tail, as well as cold-adapted hemoglobin that would better allow for oxygen transfer in the bloodstream in the cold."
Thus an Asian elephant surrogate will gestate and bear a cold-tolerant, shaggy, small-eared, short-tailed, high-domed elephant-mammoth hybrid that will look "very similar" to a real woolly mammoth.