The Vikings will need to find other ways to pester Aaron Rodgers up the middle without Tom Johnson.
Johnson, the slithery pass-rushing defensive tackle, is among the Vikings' leaders in quarterback hits, even though he had only two sacks in 14 games. He racked up four of their eight hits on Rodgers during the Vikings' 17-14 win over the Packers on Sept. 18.
The Vikings will be without Johnson on Saturday at Green Bay because he suffered a season-ending hamstring injury against Indianapolis on Sunday.
"He's a big key to our defense as far as pass rush and being able to have some depth in the rotation," defensive end Brian Robison said. "Obviously that's going to be very missed."
Johnson, who has played 51 percent of snaps this season, was a primary reason the Vikings could withstand the loss of Sharrif Floyd. They've leaned on Johnson and Robison to create an interior push, which has helped produce 35 sacks this season.
But Robison's plate is nearly full, having already moved to a tackle role on passing downs last season after injuries to Floyd and Linval Joseph. Robison, 33, is on pace to play at least 75 percent of snaps for a sixth consecutive season.
With two of their best pass-rushing tackles on injured reserve, the Vikings will turn to third-year run stopper Shamar Stephen and newcomer Toby Johnson, who initially made the practice squad this season.
"We're going to have to continue to find some more ways," coach Mike Zimmer said.