Scott LeDoux fought for boxing's world heavyweight championship and went toe to toe with Muhammad Ali, George Foreman and Mike Tyson. But LeDoux now faces his greatest opponent -- and his ring is shrinking and there is no known defense.
"I'm living with ALS," LeDoux, 60, said recently, "but I'm not going to die from it. This is my real heavyweight championship fight."
An Anoka County commissioner and executive director of the state commission overseeing boxing and related sports, LeDoux once laced up his gloves against boxing's legends. Now, he can't lace his shoes.
The massive hands that knocked down former champion Ken Norton in 1979 have weakened so badly that LeDoux recently needed help opening a packet of sweetener. He presses on his once massive triceps -- arms that powered him to a draw in his 1977 bout with soon-to-be-crowned champion Leon Spinks -- and says he feels nothing but bone. His legs tire easily; a recently acquired walker looms prominently in his future, he said.
Amyotrophic lateral sclerosis (ALS), commonly known as Lou Gehrig's disease, is a progressive, usually fatal neurodegenerative disease that plays havoc with nerve cells in the brain and spinal cord. Motor neurons, or cells, run from the brain to the spinal cord and from the spinal cord to the body's muscles. When the ALS kills the motor neurons, the body can no longer control muscles because impulses to muscle fibers are no longer being sent.
"The average survival after diagnosis is three years," said Dr. Eric Sorenson, a Mayo Clinic specialist. "There are people who will fight till their last breath, but the fatality rate is 95 percent."
He noted that Stephen Hawking, 67, the famed British theoretical physicist, was first diagnosed with ALS 40 years ago. "But," said Sorenson, "I don't know of another case like his."
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