FOCUS ON FIVE STORY LINES
1 Tiebreaker in the East Cowboys at Eagles
Philadelphia has a chance to sweep the season series and take a one-game lead in the NFC East with a victory, but Dallas has some extra rest after playing a Thursday night game.
2 West Coast wipeout? 49ers at Seahawks
San Francisco is in free fall, and this "rematch" of last year's NFC title game has all the makings of a rout by Seattle. Does that seal Jim Harbaugh's fate?
3 Giving Peyton a rest Broncos at Chargers
Denver has been winning behind the running attack, led by C.J. Anderson (pictured), which takes pressure off Peyton Manning. The Ponies have a pretty good run defense as well. San Diego is eager to make a statement, or will it be a last testament?
4 Will lightning strike twice? Dolphins at Patriots
New England can clinch the AFC East with a victory, but the Dolphins are a desperate team that has already handed the Pats a loss.
