Can too much sugar dull the brain?

Study of rats shows brain decline.

May 16, 2012 at 3:46PM
(The Minnesota Star Tribune)
(The Minnesota Star Tribune)

Eating too much sugar can eat away at your brainpower, according to scientists who showed how a steady diet of high-fructose corn syrup sapped lab rats' memories.

Researchers at the University of California Los Angeles fed two groups of rats a solution containing high-fructose corn syrup -- a common ingredient in processed foods -- as drinking water for six weeks. One group of rats was supplemented with brain-boosting omega-3 fatty acids in the form of flaxseed oil and docosahexaenoic acid (DHA), while the other group was not.

Before the sugar drinks began, the rats were enrolled in a five-day training session in a complicated maze. After six weeks on the sweet solution, the rats were then placed back in the maze to see how they fared.

"The DHA-deprived animals were slower, and their brains showed a decline in synaptic activity," said Fernando Gomez-Pinilla, a professor of neurosurgery at the David Geffen School of Medicine at UCLA.

A closer look at the rat brains revealed that those who were not fed DHA supplements had also developed signs of resistance to insulin, a hormone that controls blood sugar and regulates brain function. "Because insulin can penetrate the blood-brain barrier, the hormone may signal neurons to trigger reactions that disrupt learning and cause memory loss," Gomez-Pinilla said.

"Our study shows that a high-fructose diet harms the brain as well as the body. This is something new."

Read more from AFP.

about the writer

about the writer

Colleen Stoxen

Deputy Managing Editor for News Operations

Colleen Stoxen oversees hiring, intern programs, newsroom finances, news production and union relations. She has been with the Minnesota Star Tribune since 1987, after working as a copy editor and reporter at newspapers in California, Indiana and North Dakota.

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