Serena Williams vs. Angelique Kerber

Time: 2 a.m. Saturday

TV: ESPN (replays are available on Tennis Channel and ESPN2).

Head-to-head: Williams is 5-1 against Kerber, whose lone victory was 6-4, 6-4 in the Cincinnati Masters quarterfinals in 2012.

World rankings: Williams 1, Kerber 6.

Australian Open seeds: Williams 1, Kerber 7.

The skinny: If Williams, a 34-year-old American and six-time Australian Open champion, wins she will equal Steffi Graf's 22 major singles titles, a record in the Open era and the second-most in history behind Margaret Court's 24. Kerber, a 28-year-old German, has won seven WTA titles and has been a semifinalist in Grand Slams two other times — in 2011 at the U.S. Open and in 2012 at Wimbledon — losing both.