Big Ten football picks: Everything on the line in Week 14

Michigan vs. Ohio State is the biggest game of the college football weekend, but the Oregon-Washington showdown is just as hated with high stakes.

The Minnesota Star Tribune
November 27, 2025 at 7:00PM
The country will be tuned in when No. 1 Ohio State travels to face No. 15 Michigan in a massive and hated rivalry showdown on Saturday, while No. 6 Oregon heads north to face its hated rival in Washington. (Jay LaPrete/The Associated Press)

Will it be Ohio State vs. Indiana for the Big Ten championship? Oregon vs. Ohio State? Or even Michigan vs. Indiana? Welcome to the final weekend of college football’s regular season. In the Big Ten, Ohio State at Michigan, as usual, is the biggest game on the schedule. But don’t forget Oregon at Washington.

(Note: All games Saturday unless designated. Ratings are CFP. The Gophers-Wisconsin pick will run in the GameDay package):

Three with intrigue

No. 1 Ohio State at No. 15 Michigan | 11 a.m. | FOX

  • The Buckeyes will welcome back dynamic wideouts Jeremiah Smith and Carnell Tate from a week off to rest. They should help supply enough offense for Ohio State’s marvelous defense — which allows 7.6 points per game — to subdue the Wolverines and prevail in this rivalry for the first time since 2019. (COVID-19 wiped out the 2020 game). Ohio State 24, Michigan 10

    No. 6 Oregon at Washington | 2:30 p.m. | CBS

    • The Huskies are a handful when playing at home, but the Ducks have too many weapons — especially QB Dante Moore and TE Kenyon Sadiq — to mess this one up. Oregon 31, Washington 20

      Iowa at Nebraska | 11 a.m., Friday | CBS

      • The Hawkeyes have won nine of the past 10 in the Heartland Trophy rivalry, but the games have been close. The past seven have been decided by an average of 4.6 points. The edge stays with Iowa, whose four losses this season are by a combined 15 points. Iowa 20, Nebraska 13

        Keep an eye on

        No. 2 Indiana at Purdue | 6:30 p.m., Friday | NBC

        • Certainly, the Boilermakers remember the 66-0 drubbing they suffered at the hands of the Hoosiers last year in Bloomington. Problem is, they won’t be able to do a darn thing about it. Indiana 45, Purdue 10

          UCLA at No. 17 USC | 3:30 p.m. | NBC

          • This has been a tight series as of late, with USC winning seven and UCLA six in the past 13 meetings. The Trojans have too much firepower this season for a Bruins team that’s lost four straight after a three-game win streak. USC 38, UCLA 14

            And the rest

            Penn State at Rutgers | 2:30 p.m. | BTN

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            • Winner gains bowl eligibility, and Penn State’s players are rallying around interim coach Terry Smith to get the permanent job. That should be enough to turn back Rutgers. Penn State 31, Rutgers 20

              Maryland at Michigan State | 6 p.m. | FS1

              • The Terrapins have lost seven in a row. The Spartans have dropped eight straight. By rule, someone will win this game. Give it to the home team. Michigan State 24, Maryland 21

                Northwestern at Illinois | 6:30 p.m. | FOX

                • The overachieving Wildcats have been a surprise in the Big Ten this season, while the Fighting Illini suffered an upset loss to Wisconsin last week. Cats in a close one. Northwestern 27, Illinois 24

                  Season record

                  • Week 1: 18-0
                    • Week 2: 18-0
                      • Week 3: 13-2
                        • Week 4: 5-3
                          • Week 5: 5-1
                            • Week 6: 4-2
                              • Week 7: 5-3
                                • Week 8: 7-2
                                  • Week 9: 5-2
                                    • Week 10: 4-1
                                      • Week 11: 3-4
                                        • Week 12: 7-1
                                          • Week 13: 5-3

                                            • Overall record: 99-24

                                            about the writer

                                            about the writer

                                            Randy Johnson

                                            College football reporter

                                            Randy Johnson covers University of Minnesota football and college football for the Minnesota Star Tribune, along with Gophers hockey and the Wild.

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