Adrian Peterson will not suit up for the Vikings in Green Bay on Saturday.
The Vikings running back, who returned from a knee injury in Sunday's 34-6 loss to the Colts, did not practice this week. He was listed with both knee and groin injuries after seven touches in 12 snaps on Sunday.
The Vikings activated running back C.J Ham from the practice squad.
Ham joined the Vikings after a rookie camp tryout. He was signed to the practice squad after final cuts. The Minnesota native went to Duluth Denfeld High School and had 3,611 yards from scrimmage and 35 touchdowns in 43 games at Augustana College.
Safety Harrison Smith (ankle) and receiver Stefon Diggs (hip) are questionable to play after being listed as full participants during Friday's team activities.
Guard Brandon Fusco (concussion), fullback Zach Line (concussion) and receiver Laquon Treadwell (ankle) also have been ruled out for the Vikings.
Rookie second-round draft pick Mackensie Alexander was placed on season-ending injured reserve when Ham was promoted.
Alexander, a cornerback who was the 54th overall pick, played 13 games with no starts, six tackles and one pass defense. He was drafted for depth purposes and is considered the heir apparent to Captain Munnerlyn at the nickel slot corner spot. He was on the injury report this week because of an abdomen injury.