Bills offensive tackle Seantrel Henderson is being treated for Crohn’s disease and could miss the final three games of the season, The Buffalo News reported, citing an NFL source.

Henderson is a former Cretin-Derham Hall standout.

The Bills recently began listing Henderson with an “illness” on their injury report. When asked last Friday to identify the illness, coach Rex Ryan said, “I’m not going to get into that.”

According to an NFL source, Henderson, 23, has been diagnosed with Crohn’s, defined on the Mayo Clinic website as “an inflammatory bowel disease.” He has experienced severe stomach pain and has lost nearly 20 pounds, according to the source.

After Jordan Mills replaced him as a starter at right tackle for the Dec. 6 victory against Houston, Henderson was expected to see playing time in last Sunday’s loss at Philadelphia.

However, the source said, he took ill and had to be hospitalized in Philadelphia and was inactive for the game. Henderson did not return to Western New York with the team, the source said.

The Mayo Clinic website says Crohn’s disease “causes inflammation of the lining of your digestive tract, which can lead to abdominal pain, severe diarrhea, fatigue, weight loss and malnutrition.”