The Chiefs have shown they're capable of putting up plenty of points even without Patrick Mahomes, and their speed will test the Vikings secondary. But the Vikings should be able to win a shootout if one arises; Dalvin Cook could be in line for another big day against Kansas City's porous run defense.
THREE BIG STORY LINES
Moore, not Mahomes, for Chiefs?
With 2018 NFL MVP Patrick Mahomes rehabbing his dislocated knee, it's expected the Chiefs will go with Matt Moore at QB, though they activated Chad Henne off injured reserve Saturday. Moore threw for 267 yards and two TDs last week against the Packers.
Cousins looks to stay hot
After winning NFC Offensive Player of the Month honors, QB Kirk Cousins takes his success on the road against a 5-3 Chiefs team that's cranked up its blitz frequency; they've blitzed each of the past three QBs they've faced at least 30 percent of the time.
Road gantlet begins at Arrowhead
The Vikings kick off a tough second-half road schedule at one of the NFL's most imposing venues; they spent the week practicing with artificial noise that was loud enough to be heard several hundred feet from their practice facility. After K.C., they travel to Dallas.
TWO KEY MATCHUPS
Vikings CB Xavier Rhodes vs. Chiefs WR Tyreek Hill