Running back Alexander Mattison is still dealing with pain in his sprained ankle, which will force him to miss his second straight game Monday night against the Packers.

Mattison, who was not expected to play despite the Vikings listing him as questionable, practiced on a limited basis Saturday after being sidelined throughout last week. The Dec. 8 injury occurred on the first play of the Vikings' last drive against the Lions, when a defensive lineman landed on Mattison's ankle from behind.

Mike Boone, the second-year undrafted running back, will get his first NFL start against the Packers. The preseason star averaged 4.8 yards per carry in August.

Running back Dalvin Cook (chest) was ruled out on Saturday and will miss his first game of the season.

Vikings' inactives: Mattison (ankle), Cook (chest), DT Hercules Mata'afa, OT Oli Udoh, G Dru Samia, DT Jalyn Holmes and OT Aviante Collins.

The Packers defense will have defensive lineman Dean Lowry, who was listed questionable due to an ankle injury. He's active.

Packers' inactives: TE Jace Sternberger, OT John Leglue, G/T Alex Light, CB Ka'dar Hollman, CB Tony Brown, RB Dexter Williams and WR Ryan Grant.