Bills pummel Colts in Ryan's debut

• BUFFALO 27, INDIANAPOLIS 14: Tyrod Taylor engineered three touchdown drives and Rex Ryan's attacking Bills defense put the clamps on Andrew Luck in a victory over the Colts in Orchard Park, N.Y. In his first career start, Taylor went 14-for-19 for 195 yards, including a 51-yard opening touchdown pass to Percy Harvin. Boobie Dixon and rookie Karlos Williams scored touchdowns rushing to deliver Ryan a victory in his debut as Bills coach. The Bills built a 24-0 lead by scoring on four consecutive possessions into the third quarter. And Buffalo's defense did the rest. The retooled Colts offense was limited to 148 yards and nine first downs on its first five drives before scoring two touchdowns in the final 16 minutes.

• DENVER 19, BALTIMORE 13: Darian Stewart, who followed Gary Kubiak from Baltimore to Denver over the winter, snatched the ball from tight end Crockett Gillmore in the end zone with 28 seconds left to seal a victory for Peyton Manning and the host Broncos. Joe Flacco drove the Ravens to the Denver 16 in the final minute. One play before Stewart's interception, cornerback Brady Roby got a hand in Steve Smith Sr.'s face and a would-be touchdown catch bounded away from the veteran receiver.

• KANSAS CITY 27, HOUSTON 20: Alex Smith threw for 243 yards and three TDs in the first half as the visiting Chiefs beat the mistake-prone Texans. Travis Kelce caught two touchdown passes in the first quarter, the first coming after Kansas City intercepted Brian Hoyer on his first throw with Houston. Hoyer struggled in his debut before Ryan Mallett took over with about six minutes left and led Houston on two scoring drives, cutting the lead to a touchdown.

• N.Y. JETS 31, CLEVELAND 10: Ryan Fitzpatrick threw two touchdown passes and Chris Ivory ran for two scores in coach Todd Bowles' debut, and the Jets beat the Browns in East Rutherford, N.J. The Jets had five takeaways against the Browns, including an interception of Johnny Manziel. Brandon Marshall and Eric Decker had touchdown catches for the Jets, who sent the Browns to their 11th consecutive opening loss.

• CINCINNATI 33, OAKLAND 13: Andy Dalton threw for 269 yards and two touchdowns and Jeremy Hill ran for two scores to help the Bengals spoil coach Jack Del Rio's debut for the host Raiders. Dalton had it easy all day long as he faced little pressure and often had receivers running free in the Raiders secondary. He connected on two touchdown passes with tight end Tyler Eifert as the Bengals broke out to a 33-0 lead.