Only one of the eight remaining starting quarterbacks in the NFL playoffs has won a Super Bowl.
All-Pro Matthew Stafford led the Los Angeles Rams to a Lombardi trophy four years ago. He rallied them to a victory at Carolina last week to set up a divisional round matchup at Chicago on Sunday.
The Rams are 3 1/2-road favorites against the Bears on BetMGM Sportsbook. Home teams are the favorites in the other three second-round games.
Brock Purdy and the San Francisco 49ers fell short in the Super Bowl against Kansas City in overtime two years ago.
The Niners eliminated the defending champion Eagles to advance to face Seattle on Saturday night in a battle between NFC West rivals who played for the No. 1 seed in Week 18.
Josh Allen and the Bills have been knocked out of the playoffs by Patrick Mahomes and the Chiefs four times in the past five years. Buffalo's comeback win at Jacksonville sends the Bills to Denver on Saturday, aiming to get back to the AFC title game for the second straight year.
Houston's dominant defense ended Mike Tomlin's tenure in Pittsburgh and possibly Aaron Rodgers' career, giving C.J. Stroud another opportunity when the Texans play in New England on Sunday.
Caleb Williams and Drake Maye — first-round picks in 2024 — each won their first playoff game last week. Bo Nix, another first-round pick in that draft class, made the playoffs as a rookie, losing to the Bills. But the Broncos earned the AFC's No. 1 seed this season.