TAMPA, Fla. – When Tyreek Hill draws single coverage, Patrick Mahomes is going to find a way to get the ball to the Kansas City Chiefs' most explosive receiver.

Mahomes threw for 462 yards, including touchdowns of 75, 44 and 20 yards to Hill, who finished with 13 catches for 269 yards in the reigning Super Bowl champions' 27-24 victory over the Tampa Bay Buccaneers on Sunday.

"It feels good, you know, but I feel like there's still a lot of work for me to do," Hill said after going over 1,000 yards for the season.Mahomes outplayed Tom Brady to win the fourth career matchup of the NFL MVPs, completing 37 of 49 passes and holding the ball for more than 10 minutes without scoring on Kansas City's last two possessions to put the game away.

Hill benefited from Sammy Watkins' return to the Chiefs lineup after being sidelined since Week 5 because of a hamstring injury and got the best of a matchup with Bucs cornerback Carlton Davis, who often had no help trying to contain the speedy receiver.

"We don't get that a lot, especially with that guy and his ability," Mahomes said. "So when we do, we try to take advantage of it."

Hill had seven catches for 203 yards and two touchdowns in the first quarter alone, joining Qadry Ismail (210 in the third quarter on Dec. 12, 1999) and Lee Evans (205 in the first quarter on Nov. 19, 2006) as the only NFL receivers since 1980 to have 200 yards worth of receptions in a single quarter.

The fifth-year pro's last catch — an 8-yarder on third-and-7 in the final minute — gave Kansas City an opportunity to run out the clock.

"The last one, I learned a long time ago, you don't give Tom Brady another shot," Chiefs coach Andy Reid said. "That's why he's the G.O.A.T. So, don't give them the ball back."

The Chiefs (10-1) won their sixth game in a row and clinched their seventh 10-victory season in eight years under Reid. They are 6-0 on the road.

Brady completed 27 of 41 passes for 345 yards, three touchdowns and two second-half interceptions in falling to 2-2 against Mahomes, who built an early 17-0 lead and also had the Chiefs up by 17 entering the fourth quarter.

The Bucs (7-5) made it close, with Brady throwing TD passes of 31 and 7 yards to Mike Evans, but they never got the ball back after pulling within three with 4:10 to play.

"We battled back, but we left ourselves a big deficit," Brady said. "When you play a good offense we've got to do our job offensively and keep them off the field."