gameday predictions
BEST HEAD-TO-HEAD MATCHUP
Colts QB Peyton Manning vs. Steelers defense The Colts have lost their past 12 games at Pittsburgh, and it would appear Manning is in deep you-know-what today. The Colts have the NFL's worst rushing attack (70.1 yards per game) and will be asking Manning to beat a defense that ranks first in total defense and pass defense, and is second in sacks per pass play. (MC)