Thomas Rawls, RB, Seahawks: Marshawn Lynch's rookie fill-in won't play again this season after breaking his left ankle.
Sam Shields, CB, Packers: Left in the second quarter because of a concussion after hitting his head on the ground.
Tyler Eifert, TE, Bengals: The NFL leader with 12 TD catches was being evaluated for a concussion.
Bene Benwikere, CB, Panthers: Likely out for the season after breaking his left leg in the fourth quarter.
T.J. Yeldon, RB, Jaguars: Hurt his right ankle early and his right knee late, and he was on crutches after the game.
Brian Hartline, WR, Browns: Broke his collarbone, ending his season.
LeGarrette Blount, RB, Patriots: Didn't return after suffering a first-half hip injury.
Brandon Pettigrew, TE, Lions: Left because of a knee injury in the second quarter.
Charles Clay, TE, Bills: Didn't return after leaving because of a back injury.