PARIS — Joaquín Panichelli helped Strasbourg end third-place Lyon's 13-game winning streak in all competitions on Sunday.
Panichelli was a constant thorn for the Lyon defenders and the Argentine sealed Strasbourg's 3-1 home win in Ligue 1 with a late penalty.
Lyon was seeking to match its club-record 14 straight wins from the 2005-06 season.
Endrick endured a frustrating game for Lyon. The Brazilian's centrally placed shot was easily saved by Mike Penders in the second half.
To make matters worse for Lyon, Pavel Sulc had to go off injured before half an hour was played. The Czech player is the team's top scorer in the league with 10 goals this season.
Strasbourg dominated from the start and Martial Godo got the deserved opener in the 37th after Diego Moreira played him in behind the Lyon defense.
Moreira made it 2-0 early in the second half when his shot from outside the penalty area took a decisive deflection off a Lyon defender.
Tempers flared after Lyon defender Ruben Kluivert pushed Moreira in the back on the sideline. Kluivert was booked.