Mental Health 101: Battling Major Depressive Disorder

Recognizing Signs and Seeking Help

Provided by MN Mental Health Clinics

October 21, 2025 at 8:08PM

Mental health is an integral part of our overall well-being, yet it is often overlooked, ignored or denied. In this series, Minnesota Mental Health Clinics sheds light on the importance of recognizing, understanding, and addressing mental health challenges. Join us for insights and practical strategies to help you nurture a healthier mind and foster resilience.

People talk about being depressed in general terms when they feel a little down, but sometimes depression can be an illness. Major Depressive Disorder (MDD) is marked by persistent sadness, loss of interest in nearly all activities, and a range of emotional and physical symptoms that last at least two weeks. MDD is serious: it can disrupt work, relationships, sleep, appetite, and even cognitive processing, making everyday tasks feel insurmountable.

Fortunately, with a mix of professional and self-care, MDD can be treated. Early identification of depressive symptoms is vital to getting the right care in a timely manner. Untreated MDD increases risk for chronic health problems, substance misuse, and suicidal ideation. Recognizing the signs in yourself or a loved one, on the other hand, can pave the way for intervention and better recovery outcomes.

What to Know About MDD

  • Not alone: Depression is the leading cause of disability worldwide.
    • Take action to improve outcomes: Up to 80 % of individuals experience significant symptom reduction with therapy, medication, or a combination.

      Recognizing Major Depressive Disorder

      Depression can impact different people in different ways emotionally, physically, and behaviorally. It’s important to watch for any mix of these symptoms in yourself or someone close to you:

      • Persistent low mood or hopelessness
        • Loss of interest or pleasure in daily activities
          • Changes in weight or appetite
            • Insomnia or hypersomnia
              • Fatigue or low energy
                • Feelings of worthlessness or excessive guilt
                  • Difficulty concentrating
                    • Recurrent thoughts of death or suicide

                      Self-Help and Lifestyle Changes Can Help

                      For those who are experiencing MDD symptoms, even those also seeking professional help, making purposeful changes to daily routines can offer benefits. Here are four strategies to try:

                      • Behavioral Activation: Schedule small, enjoyable activities daily—including brief walks or phone calls—to counteract withdrawal.
                        • Sleep Hygiene: Set consistent sleep and wake times, limit screen use before bed, and create a calming nighttime routine.
                          • Nutrition: Incorporate omega-3-rich foods, lean proteins, and whole grains to support brain health.
                            • Physical Activity: Aim for at least 30 minutes of moderate exercise most days to boost mood and energy levels.

                              Professional Treatment Can Offer Significant Relief

                              Because of the seriousness and complexity of MDD, those diagnosed with the condition will likely benefit from professional care. This can take different forms:

                              • Psychotherapy: This may include evidence-based approaches like Cognitive Behavioral Therapy (CBT), Interpersonal Therapy (IPT), and Acceptance & Commitment Therapy (ACT).
                                • Medication: SSRIs, SNRIs, and other antidepressants, managed by psychiatric clinicians, can help manage mood and emotional impacts of depression.
                                  • Combined Care: Integration of therapy and medication often yields the best outcomes for moderate to severe MDD.

                                    Next Steps to Help Care for Mental Health

                                    The team at Minnesota Mental Health Clinics offers comprehensive MDD assessments and personalized treatment plans, blending psychotherapy, and medication management. Regular progress reviews ensure that care evolves with your needs, and we’re here to help you take the first step forward.

                                    If you’re experiencing symptoms of depression, schedule an MDD assessment today to begin your path to recovery.

                                    If you’re in crisis or need immediate help, call or text 988.

                                    Schedule a Consultation Today

                                    Disclaimer

                                    This article is for informational purposes only and should not be considered a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified health provider regarding any questions or concerns about your mental health.