Jadon Sancho scored his first goal for Aston Villa to lift his new club past Fenerbahce 1-0 and into the Europa League round of 16 on Thursday with a game to spare.
Lyon also clinched a last-16 spot with a 1-0 victory over Young Boys in Bern, and Freiburg joined them by beating Maccabi Tel Aviv by the same score.
Lyon and Villa are level on points (18) with six wins and a loss atop the standings with one game to go the in the league phase. Freiburg is one point behind in third.
Like in the Champions League, the top eight finishers advance automatically after eight rounds to the round of 16 while the teams placed from nine to 24 enter a two-leg playoff to progress.
Sancho, who joined Villa on a season-long loan from Manchester United in September, met a deflected cross from Matty Cash to hand Villa the victory.
Villa manager Unai Emery had a string of injured players unavailable, including captain John McGinn and defensive midfielder Boubacar Kamara.
Emery has won the Europa League trophy four times during stints in charge of Sevilla and Villarreal.
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