Buffalo coach Rex Ryan ruled out running back LeSean McCoy and receiver Sammy Watkins from playing against the Giants on Sunday.

Ryan initially said he'd never use the word "out" after the two players missed their second straight practice Thursday.

Then, Ryan shook his head sideways and said reporters could figure it out on their own.

McCoy is sitting out to rest a left hamstring injury that's nagged him since he was hurt Aug. 18. Watkins was sidelined after hurting his right calf in a win at Miami on Sunday.

Starting right guard John Miller (groin) missed his second straight practice. Safety Aaron Williams (neck) practiced on a limited basis, and has a chance to play after missing one game.

Guion rejoins Packers

The Packers' defensive line, instrumental in helping contain Seattle's Marshawn Lynch and Kansas City's Jamaal Charles the past two games, is about to get even stronger.

Former Viking Letroy Guion, suspended for three games for violating the NFL's substance abuse policy, returned to practice Wednesday. He practiced again Thursday and will be added to the 53-man roster in time for Sunday's game at San Francisco.

"Just from the strength and conditioning standpoint, I think he's in excellent shape," coach Mike McCarthy said. "Definitely in shape the way he was coming into camp. ... he looks good."

Cruz won't play

The return of New York Giants wide receiver Victor Cruz is on hold.

Coach Tom Coughlin says Cruz will not play Sunday against Buffalo after aggravating a calf injury Wednesday. Instead, Cruz will work with trainers. There is no timetable for his return.

Cruz had said Monday he expected to practice Wednesday and play Sunday.

Etc.

• The Jets are hoping to have Eric Decker back in the lineup in London on Sunday.The star wide receiver participated in some team drills for the first time since spraining his left knee nearly two weeks ago. Decker was hurt against Indianapolis in Week 2 and sat out last Sunday against Philadelphia. His status remained uncertain for the Jets' game against the Dolphins on Sunday in London.

•The Bears are preparing for the possibility that quarterback Jimmy Clausen must start Sunday against the Raiders, while hoping Jay Cutler continues to heal quickly from the strained hamstring he suffered Sept. 20. A decision on Cutler's availability appears increasingly likely to be finalized Sunday morning.

•Falcons coach Dan Quinn said he expects receiver Julio Jones will be "ready to rock" on Sunday against the Texans despite a new toe injury. Jones had only limited participation in Thursday's practice after being held out Wednesday.

•Jaguars should defensive end Andre Branch (knee) made it through a second straight practice without any setbacks, clearing the way for him to make his season debut at Indianapolis on Sunday.

•Hall of Famer Warren Sapp took a plea deal that spares him jail time in a case involving a scuffle with his former girlfriend that began after margaritas at a casino hotel swimming pool.

The former Buccaneers and Raiders defensive tackle pleaded no contest in Las Vegas Justice Court to one misdemeanor domestic violence charge.