– Aaron Rodgers' remarkable run of mistake-free football at home is over. Green Bay, though, is still perfect this season.

A relentless defense helped the Packers overcome an unusually average day from their MVP quarterback.

Rodgers threw for two touchdowns and 241 yards, and the defense had three sacks and four interceptions to hold off the St. Louis Rams for a 24-10 victory on Sunday.

"Good team win today, start with the defense," coach Mike McCarthy said. "… They were clearly the key to our victory."

Rodgers was 19-for-30 with long scoring strikes to receivers Ty Montgomery and James Jones for the Packers (5-0).

Since becoming the starting quarterback in 2008, Rodgers has 31 touchdown passes of at least 50 yards, the most in the NFL over that span.

But NFL-record streaks of 587 pass attempts and 49 touchdown passes at home without an interception for Rodgers ended in the first quarter on former Wayzata star linebacker James Laurinaitis' diving pick of a tipped ball for the Rams (2-3).

Rodgers threw another interception in the second quarter before losing a fumble in the third on a sack.

"All of them," Rodgers said when asked which turnover bothered him the most.

The Packers defense made up for the turnovers. Relentless pressure on Rams quarterback Nick Foles led to a career-worst four interceptions, with two in the fourth quarter inside the Packers 10.

The Green Bay defense held up in spite of losing tackle B.J. Raji to a groin injury and linebacker Nick Perry to a shoulder injury. Guard T.J. Lang also left in the first quarter because of a knee injury.

Star linebacker Clay Matthews set the tone with 1½ sacks and several other trips into the backfield. Mike Daniels led the charge on the defensive line with eight tackles. Safeties Ha Ha Clinton-Dix and Micah Hyde more than made up for the loss of the injured Morgan Burnett.

"It still is an offensive team, but it's nice when the defense can hold their own," Matthews said.