SAN DIEGO — Even with no fans in the stands, rookie Jake Cronenworth got a sense of the San Diego Padres' rivalry with the Los Angeles Dodgers.

Cronenworth singled home the go-ahead run in the sixth inning for the Padres, who hit three solo homers off Walker Buehler and beat the Dodgers 5-4 on Monday night.

"If I didn't know before today there was a rivalry, I definitely do know now," said Cronenworth, whose hit gave ace Chris Paddack his first career win against Los Angeles.

"It's fun to play in those type of games. I never played in major league playoff baseball but if I had to guess, that was like it. It was fun. Guys were talking back and forth. It was great."

Cronenworth also turned in several nice plays at first base, where he made his fifth start. First baseman Eric Hosmer is on the injured list with a stomach ailment.

Trent Grisham, Wil Myers and Fernando Tatis Jr. homered for San Diego.

"Just three so-so pitches that they took advantage of," Buehler said.

Paddack (2-0) allowed three runs and five hits in six innings, struck out five and walked none. His previous three starts against Los Angeles were at Dodger Stadium last year as a rookie. He went 0-1 in those games.

Buehler gave up three home runs for just the second time in his career. He left after five innings with the score tied at 3 after yielding three hits while striking out three and walking three.

"I thought overall, very positive. We got the pitch count up, got him through five," Dodgers manager Dave Roberts said.

"I just don't think that he had his command that he will have. It's his second start of the year. So, he's going to be fine and I think now we can kind of loosen the reins more his next turn and win a baseball game his next turn."

Brusdar Graterol (0-2) relieved Buehler to open the sixth and permitted a single by Manny Machado, who advanced on Tommy Pham's grounder. Cronenworth singled to bring in Machado for a 4-3 lead. Cronenworth later scored on Austin Hedges' two-out single, the first time the catcher reached safely this season.

Padres manager Jayce Tingler said Cronenworth was "super impressive. That's from the get-go, I thought he was really good in the box. Even the at-bats he didn't get hits in, I just thought he was a threat up there. He looked comfortable, to be able to lace a line drive over shortstop. And then it was two or three kind of game-saving defensive plays. ... He was outstanding tonight."

Cronenworth made his major league debut on July 26. He was obtained with Pham in an offseason trade with Tampa Bay that sent Hunter Renfroe to the Rays.

Reigning NL MVP Cody Bellinger homered off Kirby Yates leading off the ninth before the closer struck out three batters for his first save this year. Yates led the majors with 41 saves last season.

It was the first meeting of the year between the seven-time defending NL West champion Dodgers and the Padres, who think they're built for success in the pandemic-shortened 60-game season. Los Angeles went 13-6 against San Diego last year.

"This is a very talented offensive club," Roberts said about the Padres. "They're playing well, they've got a lot of confidence, so this was no surprise."

Joc Pederson homered to left-center on Paddack's first pitch, his first of the season and his 21st career leadoff homer.

Grisham homered to right with one out in the bottom of the inning, his fourth. Myers homered to right-center with two outs it the fourth, his third, for a 2-1 lead.

"Just not enough strikes, not enough good counts for me," Buehler said. "Got to get in the zone more and start getting in better counts."

The Dodgers regained the lead on Will Smith's two-run double to right-center with one out in the fifth. Corey Seager was aboard on a leadoff double and Matt Beaty on a single.

Tatis tied it with a shot to right with two outs in the fifth, his third. Tatis hit a tying solo homer in the ninth inning at Colorado on Friday night. Pham later hit a three-run drive and the Padres won 8-7.

TRAINER'S ROOM

Dodgers: OF Mookie Betts was out of the lineup for the first time this season with a finger injury sustained during an at-bat Sunday at Arizona. Roberts said the swelling in the finger was still substantial. "Hopefully we'll see how he feels tomorrow and see if we can get him in there," Roberts said.

UP NEXT

Dodgers: RHP Dustin May (0-0, 2.35 ERA) makes his third start of the season. He is 0-2 with a 3.46 ERA and nine strikeouts in four career appearances against San Diego.

Padres: RHP Dinelson Lamet (1-0, 1.80) is scheduled to make his third start.