Rich Hill's lingering blister made Dave Roberts sick.
Roberts made the decision to pull Hill after seven perfect innings in the Los Angeles Dodgers' 5-0 victory over the host Miami Marlins on Saturday night.
Hill (12-3) had thrown 89 pitches and struck out nine when Roberts replaced the 35-year-old lefthander with Joe Blanton at the start of the eighth.
"I feel sick to my stomach," said Roberts, trying to lead Los Angeles to the NL West title in his first year as Dodgers manager. "Rich had an opportunity of a lifetime. You take the personal aside. As a manager you are taking a lot of information.
"We have been dealing with Richie's blister and that caused him to miss a lot of time."
Hill didn't pitch in the majors between May 29 and July 2 because of a strained left groin and between July 17 and Aug. 24 because of a blister on the middle finger of his left hand. He has pitched 19 scoreless innings since joining the Dodgers after an Aug. 1 trade with Oakland.
Hill felt he could have continued pitching. "Obviously, I didn't want to come out of the game," he said. "But I think there is a bigger picture here and we all know what it is. Dave was in a very difficult position. You look at it and move on. That's all you can do."
Blanton retired his first two batters before Jeff Francoeur singled to left off shortstop Corey Seager's glove. There has never been a combined perfect game in the majors.