The Vikings could be without six starters for Thursday’s game against the Washington Redskins.

Four starters were declared out on the final injury report issued Wednesday: right tackle Phil Loadholt (concussion), tight end Kyle Rudolph (fractured foot), safety Jamarca Sanford (groin) and cornerback Chris Cook (hip).

Running back Matt Asiata (shoulder) and nose tackle Fred Evans (knee) also were ruled out.

Starting nose tackle Letroy Guion (chest/knee) and left guard Charlie Johnson (elbow) were listed as doubtful, meaning there’s only 25 percent chance they will play.

Tight end Rhett Ellison (ankle) is questionable.

The secondary has been hit especially hard by injuries. Without their starting safeties — Sanford and Harrison Smith (turf toe) — the Vikings will rely on a rotation of Andrew Sendejo, Mistral Raymond and Robert Blanton.

Raymond struggled in the loss at Dallas on Sunday. Defensive coordinator Alan Williams said Raymond will start again Thursday night, but he will continue to rotate with Blanton. Raymond played 38 snaps against Dallas, Blanton 33.

At cornerback, Cook will miss his second consecutive game because of the hip injury. That means Cook will have missed more games (29) than he’s played (28) in his four seasons because of injuries and legal issues.

Rookie cornerback Xavier Rhodes (shoulder) and starter Josh Robinson (chest) also were on the injury report this week, but both had full participation on Wednesday and were listed as probable.