ROSMALEN, Netherlands — John Isner was one of four seeded men's players to lose in the first round at the rain-interrupted Topshelf Open.
The third-seeded American lost 6-7 (3), 6-3, 6-4 to Evgeny Donskoy on Monday. No. 6 Marcos Baghdatis of Cyprus, No. 7 Victor Hanescu of Romania and No. 8 Daniel Gimeno-Traver of Spain were also upset.
Donskoy earned breaks against the big-serving Isner early in the second set and again in the final set to advance at the Wimbledon warm-up.
Carlos Berlocq beat Baghdatis 6-2, 6-4. Hanescu lost 6-4, 6-3 to Guillermo Garcia-Lopez, and Andrey Kuznetsov beat Gimeno-Traver 7-6 (4), 6-3.
Defending champion David Ferrer, the French Open runner-up, opens play Tuesday against Xavier Malisse.
In the women's event, second-seeded Dominika Cibulkova beat Lourdes Dominguez Lino 6-1, 6-7 (5), 7-6.
Third-seeded Carla Suarez Navarro advanced with a 6-3, 6-2 win over Johanna Larsson, and Lauren Davis of the United States defeated Andrea Hlavackova 6-3, 6-4.
|Kansas City - J. Guthrie||5:10 PM|
|Cleveland - T. Bauer|
|Toronto - D. Hutchison||5:10 PM|
|Boston - C. Buchholz|
|Tampa Bay - J. Odorizzi||6:05 PM|
|NY Yankees - C. Whitley|
|Washington - A. Cole||6:10 PM|
|Atlanta - J. Teheran|
|NY Mets - R. Montero||6:10 PM|
|Miami - D. Phelps|
|Milwaukee - K. Lohse||6:10 PM|
|Cincinnati - J. Cueto|
|Pittsburgh - J. Locke||7:05 PM|
|Chicago Cubs - T. Wood|
|Seattle - J. Happ||7:05 PM|
|Texas - R. Detwiler|
|Detroit - A. Sanchez||7:10 PM|
|Minnesota - M. Pelfrey|
|Philadelphia - S. Gonzalez||7:15 PM|
|St. Louis - M. Wacha|
|Colorado - K. Kendrick||8:40 PM|
|Arizona - A. Bradley|
|LA Angels - J. Weaver||9:05 PM|
|Oakland - S. Gray|
|Houston - R. Hernandez||9:10 PM|
|San Diego - T. Ross|
|San Francisco - M. Bumgarner||9:10 PM|
|Los Angeles - C. Kershaw|
|San Antonio||9:30 PM|