UnitedHealth's $4.9 billion acquisition of Brazilian health care company Amil is the second-largest in its history.

Date

CompanyannouncedValue

Pacificare Health Systems Inc.7/6/2005$7.1 billion

Amil Participacoes SA10/8/2012$4.9 billion

Oxford Health Plans LLC04/26/2004$4.8 billion

Mid Atlantic Medical Service10/27/2003$3.1 billion

Sierra Health Services Inc.3/12/2007$2.5 billion

Source: Bloomberg News