A look President Obama's second-term Cabinet:
Hillary Rodham Clinton is expected to leave soon.
Nominated: Sen. John Kerry is expected to be quickly confirmed. His confirmation process begins Thursday.
Timothy Geithner is expected to leave at the end of the month.
Nominated: White House Chief of Staff Jack Lew.
Leon Panetta is likely to leave in mid-February, if his replacement is confirmed.
Nominated: Chuck Hagel, a former Republican senator, is facing opposition from fellow Republicans because of his positions on Iran -- he opposed unilateral sanctions -- and Israel. His confirmation hearings begin Jan. 31.
Eric Holder will remain, although it remains unclear how long he will stay.
Former Sen. Ken Salazar announced this month that he would leave by the end of March to return home to Colorado.
Contenders: Names on the shortlist include Deputy Interior Secretary David Hayes, former Sen. Byron Dorgan, former Wyoming Gov. Dave Freudenthal and Washington Gov. Chris Gregoire.
Jack Lew has been nominated to be Treasury secretary.
Expected nomination: Denis McDonough, Deputy National Security Adviser and a native of Stillwater, Minn., is expected to be named this week. The job does not require confirmation.
Thomas Vilsack confirmed last week that he is staying.
Hilda Solis announced her resignation in a surprise letter on Jan. 9. She provided no date when she would step down. She is expected to return to her native California and run for a seat on the Los Angeles County Board of Supervisors.
Contenders: No potential replacement have been identified.
Ray LaHood, a Republican, said he remains open to staying, but has not confirmed his plans.
Former Kansas Gov. Kathleen Sebelius will stay on. She is expected to see through the implementation of the health care overhaul.
Steven Chu, a Nobel Prize-winning physicist, has not confirmed his plans.
Shaun Donovan will stay on. He is expected to play a central role in the administration's efforts to keep the Federal Housing Administration solvent.
Arne Duncan will stay on.
Eric Shinseki will remain.
Janet Napolitano will stay. A former governor of Arizona, she may play an important role in Obama's push for immigration legislation, a high early priority for the administration.
Rebecca Blank, acting secretary. John Bryson resigned from the job in June after taking a medical leave of absence. The agency may be targeted to be combined with other agencies, Blank said.