Betsy Palmer, 88, an actress who started out as a game show panelist and worked in serious theater but achieved her greatest fame as a slasher and ax murderer in "Friday the 13th," has died. She died Friday at a hospice near her home in Danbury, Conn.

In the horror film "Friday the 13th" (1980), Palmer portrayed Pamela Voorhees, a summer-camp cook with a penchant for impaling the counselors.

Although she later attended numerous horror film fan conventions, she told interviewers that she hated the script and refused to act in the film's many sequels.

She took the job, she said, because it required only 10 days of work and would earn her $10,000 — just what she needed to replace the aging Mercedes that quit on her one terrible night as she drove on busy Interstate 95. She replaced it with a Volkswagen Sirocco.

Born Patricia Betsy Hrunek in East Chicago, Ind., on Nov. 1, 1926, Palmer studied at DePaul University before heading for the Actors Studio in New York. She had dramatic roles on respected television shows including "Playhouse 90" and "Studio One" in the 1950s. In 1953, she appeared on a new game show called "Wheel of Fortune" as the letter-turner — the original Vanna White, as she later recounted it.

Her film work included "Mr. Roberts" with Henry Fonda, "The Long Gray Line" with Tyrone Power and Maureen O'Hara, "Queen Bee" with Joan Crawford and "The Tin Star" with Fonda and Anthony Perkins.

Meanwhile, she did stints on the "Today" show and became a long-running celebrity panelist on the quiz show "I've Got A Secret."

Her other TV credits included "Knot's Landing," "The Love Boat," "Newhart," "Just Shoot Me" and "Murder, She Wrote."

Irwin Rose, 88, a biochemist who shared the 2004 Nobel Prize in chemistry for discovering a way that cells destroy unwanted proteins — the basis for developing new therapies for diseases such as cervical cancer and cystic fibrosis — died in his sleep Tuesday in Deerfield, Mass.

Rose had a "formidable intellect and unwavering curiosity about fundamental biological and chemical processes that are the foundation for life," said Chancellor Howard Gillman at the University of California, Irvine, in a statement.

Each human cell contains about 100,000 different proteins, which carry out jobs such as speeding up chemical reactions and acting as signals.

Rose, along with Israelis Aaron Ciechanover and Avram Hershko, won the Nobel for discovering how plant and animal cells marked old and damaged proteins with a "kiss of death" molecule — the polypeptide ubiquitin. The proteins are then chopped to pieces.

John R. Allen, 69, a Washington Post editor who in 34 years with the newspaper helped design the layout of stories on page one, as well as pages in the Metro, Style and Sports sections, died Sunday in New York.

His wife, Jo Rector Allen, said he was stricken with symptoms consistent with a pulmonary embolism or a heart attack.

Allen joined the Post in 1969 as a copy editor, and he retired in 2003 as deputy news editor. His career spanned an era of change in the technology of producing a daily newspaper, the evolution of hot type to cold type and the use of computers to produce a printed paper.

Ed Thiede, a Post news projects editor, wrote in an announcement that Allen "helped guide the newspaper from the days of paste-up and black-and-white images through the launch of electronic pagination and color photography and into the days when the Metro section was zoned three ways every day."

John Robert Allen was born in Omaha on Nov. 27, 1945.

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