Whitney Mercilus, LB, Texans His spin move to slip through the Jaguars line resulted in a strip sack of Gardner Minshew that led to Houston's lone touchdown.
Matt Breida, RB, 49ers Filling in for an injured Tevin Coleman, he set up his teammates' five touchdowns with 132 yards of offense on only 12 carries and a reception.
Demarcus Robinson, WR, Chiefs The biggest beneficiary of Patrick Mahomes' arm in Week 2, he had six catches for 172 yards and two touchdowns at Oakland.
Adoree' Jackson, DB, Titans He dragged down Deon Cain by the helmet on a deep pass well before the ball's arrival, a 46-yard pass interference call to set up the Colts' first score.
Donte Moncrief, WR, Steelers After dropping four passes in Week 1, he had only one drop Sunday, but it was deflected and intercepted, setting up the Seahawks' go-ahead TD.
Ty Long, P/K, Chargers It's not fair he is being asked to both kick and punt with Mike Badgley hurt. But he is, and he missed field-goal attempts of 39 and 41 yards.
Going up Tight end Mark Andrews has emerged as one of Lamar Jackson's favorite targets, with consecutive games of eight receptions, at least 100 yards and one TD.
Going down We are guessing people will do this anyway, but if you have rolled the dice with Mitchell Trubisky at QB the first two weeks, maybe it's time to try someone else.
Looking ahead Tyreek Hill had a big game last year when the Chiefs beat the Ravens in OT at home, but he's hurt this time, so Patrick Mahomes will have to turn elsewhere.