Among the myriad Twitter feuds you might never have imagined, the odd case of mouthy Minneapolis rapper Prof vs. hunky “Full House” and “ER” actor John Stamos might take the cake.

After two years of ironic, stalker-like tweets trying to get a rise out of Stamos, Prof finally got his attention in a big way. The tipping point was a tweet that apparently suggested the actor famous for his “uncle” character is into children in a perverted way.

Prof said he doesn’t remember sending the tweet, which happened about two months ago, and can’t find it now — “Let’s face it: I was probably drunk,” the rapper said Friday — but Stamos certainly did remember it. He sent out several vehement tweets on the matter Thursday.

“U do pediphile [sic] jokes I’ll kill you,” read one of the messages from the @JohnStamos account, which has nearly 1.4 million followers, compared to almost 15,000 for @Profgampo — although that number could go up significantly as a result of the feud.

Prof and Stamos finally connected by phone late Thursday night and talked for about a half-hour, according to the rapper. It was tense at first, he said.

“He told me he was lawyering up,” Prof claimed, admitting that threat scared him: “I really don’t know if I did break the law or not. Maybe.”

Eventually, however, things were smoothed over — at least enough for Stamos to back off his legal threats, Prof said.

The actor’s New York publicist declined to verify details of the conversation or comment on the Twitter exchange, but Stamos himself confirmed the phone call on Twitter. Pointing to his 28-year dedication to Phoenix-based abuse resource center Childhelp, he sent out a tweet Friday morning:

“@Profgampo and me going to shoot fun video — was hurt being called pedophile — all the work i do for kids @Childhelp he apologized like a man.”

Prof also sent out a conciliatory tweet:

“Had a half hour conversation w @JohnStamos. Believe it or not, he is a REAL MAN. We ironed out our differences, & are now BFFs once again.”

Prof later applauded Stamos for “being a good sport about it and not turning it into a Hollywood lawyer thing.” However, the real-life Jacob Anderson — who sold out a 4,000-capacity concert on Minneapolis’ West Bank last summer with a stage act based on crude humor and a tacky personality — also made it clear he does not intend to stop what he called “a comical obsession” over the actor.

“It’s an intense relationship; we’re sort of still in the newlywed stage,” he quipped, adding with no sense of irony. “This is really a dream come true of mine.”