Botox may be used to treat people with an overactive bladder when other treatments for the conditions have failed, the U.S. Food and Drug Administration said.

Overactive bladder involves sudden bladder contractions and an urgent need of urination.

Botox is made from a toxin produced by the bacterium Clostridium botulinum. The drug is used in small doses to temporarily remove facial wrinkles, underarm sweating, correct misaligned eyes etc.

Botox injection can let the muscles of the bladder relax, thus increasing the capacity of the bladder to store urine and reducing urinary incontinence. A procedure called cystoscopy is used to inject Botox in the bladder, FDA said.

"Clinical studies have demonstrated Botox's ability to significantly reduce the frequency of urinary incontinence. Today's approval provides an important additional treatment option for patients with overactive bladder, a condition that affects an estimated 33 million men and women in the United States," said Hylton V. Joffe, M.D., director of the Division of Reproductive and Urologic Products in FDA's Center for Drug Evaluation and Research.


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